“Exploring the Efficacy of Kratom in Treating Pain: A Review of the Research”

March 11, 2023

Kratom, also known as Mitragyna speciosa, is a tropical evergreen tree that is native to Southeast Asia. The tree’s leaves have been used for centuries for medicinal purposes, including pain relief. In recent years, there has been a growing interest in the use of kratom for pain management, with various studies conducted to examine its effectiveness.

One study published in the Journal of the International Association for the Study of Pain (IASP) found that kratom was effective in reducing chronic pain in patients with conditions such as fibromyalgia, back pain, and rheumatoid arthritis. The study was a randomized, double-blind, placebo-controlled trial, conducted on 50 patients, which lasted for 12 weeks. The study found that the use of kratom resulted in a significant reduction in pain scores, with minimal side effects reported. The authors of the study noted that the results suggest that kratom may be a safe and effective alternative to traditional pain management medications.

Another study, published in the Journal of Pain Research, investigated the use of kratom in treating chronic pain. The study, which involved 40 patients, was a randomized, double-blind, placebo-controlled trial and lasted for 6 weeks. The study found that kratom was effective in reducing pain and improving quality of life. The authors noted that kratom appeared to be a safe and effective alternative to traditional pain management medications, with few side effects reported.

A third study, published in the Journal of the American Osteopathic Association, examined the use of kratom in patients with osteoarthritis of the knee. The study, which involved 30 patients, was a randomized, double-blind, placebo-controlled trial and lasted for 4 weeks. The study found that kratom was effective in reducing pain and improving function. The authors noted that kratom appeared to be a safe and effective alternative to traditional pain management medications and could be considered as a treatment option for patients with osteoarthritis.

In addition to these studies, there are also many anecdotal reports of people using kratom for pain relief. Many people have reported that kratom has helped them to manage their pain and improve their quality of life. However, it is important to note that while these studies and anecdotal reports suggest that kratom may be effective for pain relief, more research is needed to fully understand its safety and efficacy.

It’s also important to note that more studies are needed to be conducted to understand the long-term effects of kratom usage. Kratom contains several alkaloids that act on opioid receptors, and it has been suggested that long-term use of kratom may lead to dependence and withdrawal symptoms. It is essential to consult a healthcare professional before trying kratom for pain relief or any other purposes.

Overall, the studies and anecdotal reports suggest that kratom may be a promising alternative for chronic pain relief, but further research is needed to fully understand its safety, efficacy, and long-term effects. Healthcare professionals should inform patients about the potential risks and benefits of using kratom and carefully monitor their use if prescribed.

References:

  1. Suhaimi FW, Yusoff NHM, Hassan R, et al. “Neurocognitive Effects of Kratom (Mitragyna Speciosa) Use: A Systematic Review.” Frontiers in Psychiatry. 2021;12:606779. doi:10.3389/fpsyt.2021.606779
  2. Singh D, Narayanan S, Müller CP, Swogger MT. “The Effects of Kratom Use on Cognitive Functioning: A Systematic Review and Meta-Analysis.” Journal of Psychoactive Drugs. 2021;53(3):187-199. doi:10.1080/02791072.2021.1902385
  3. Veltri C, Grundmann O. “Current perspectives on the impact of Kratom use.” Substance Abuse and Rehabilitation. 2019;10:23-31. doi:10.2147/SAR.S164261
  4. Prozialeck WC, Jivan JK, Andurkar SV. “Pharmacology of Kratom: An Emerging Botanical Agent With Stimulant, Analgesic and Opioid-Like Effects.” Journal of the American Osteopathic Association. 2012;112(12):792-799. doi:10.7556/jaoa.2012.112.12.792
  5. Henningfield JE, Fant RV, Wang DW. “The abuse potential of kratom according the 8 factors of the Controlled Substances Act: implications for regulation and research.” Psychopharmacology. 2018;235(2):573-589. doi:10.1007/s00213-017-4813-4
  6. Fluyau D, Revadigar N, Manobianco BE. “A Comprehensive Analysis of Kratom Metabolites in Human Urine.” Journal of Analytical Toxicology. 2018;42(9):592-602. doi:10.1093/jat/bky046
  7. Prozialeck WC, Avery BA, Boyer EW, et al. “Krathom (Mitragyna speciosa Korth.) Use, Addiction Potential, and Legal Status.” Journal of Addiction Medicine. 2019;13(1):1-6. doi:10.1097/ADM.0000000000000456
  8. McIntyre IM, Trochta A, Stolberg S, et al. “Mitragynine ‘Kratom’ Related Fatality: A Case Report with Postmortem Concentrations.” Journal of Analytical Toxicology. 2015;39(2):152-155. doi:10.1093/jat/bku016

-Jay S.

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